Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets

AIMS/HYPOTHESIS: Pro-atherogenic and pro-oxidant, oxidised LDL trigger adverse effects on pancreatic beta cells, possibly contributing to diabetes progression. Because oxidised LDL diminish the expression of genes regulated by the inducible cAMP early repressor (ICER), we investigated the involvemen...

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Main Authors: Favre, D., Niederhauser, G., Fahmi, D., Plaisance, V., Brajkovic, S., Beeler, N., Allagnat, F., Haefliger, J. A., Regazzi, R., Waeber, G., Abderrahmani, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149674/
https://ncbi.nlm.nih.gov/pubmed/21547497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2165-x
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