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Is CFTR-delF508 Really Absent from the Apical Membrane of the Airway Epithelium?
BACKGROUND: Understanding where mutant CFTR is localised in airway epithelia is essential in guiding the best therapeutic approach to correct the dysfunction of the CFTR protein. The widely held paradigm is that CF patients harbouring the commonest mutation, CFTR-delF508, trap CFTR within the endopl...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149652/ https://ncbi.nlm.nih.gov/pubmed/21826241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023226 |
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