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Evidence for a Two-Metal-Ion Mechanism in the Cytidyltransferase KdsB, an Enzyme Involved in Lipopolysaccharide Biosynthesis

Lipopolysaccharide (LPS) is located on the surface of Gram-negative bacteria and is responsible for maintaining outer membrane stability, which is a prerequisite for cell survival. Furthermore, it represents an important barrier against hostile environmental factors such as antimicrobial peptides an...

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Bibliografiske detaljer
Main Authors: Schmidt, Helgo, Mesters, Jeroen R., Wu, Jing, Woodard, Ronald W., Hilgenfeld, Rolf, Mamat, Uwe
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149649/
https://ncbi.nlm.nih.gov/pubmed/21826242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023231
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