Recombinant VP1, an Akt Inhibitor, Suppresses Progression of Hepatocellular Carcinoma by Inducing Apoptosis and Modulation of CCL2 Production

BACKGROUND: The application of viral elements in tumor therapy is one facet of cancer research. Recombinant capsid protein VP1 (rVP1) of foot-and-mouth disease virus has previously been demonstrated to induce apoptosis in cancer cell lines. Here, we aim to further investigate its apoptotic mechanism...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Tai-An, Wang, Jui-Ling, Hung, Shao-Wen, Chu, Chiao-Li, Cheng, Yung-Chih, Liang, Shu-Mei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149645/
https://ncbi.nlm.nih.gov/pubmed/21826248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023317
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