Dipeptidyl Peptidases as Survival Factors in Ewing Sarcoma Family of Tumors: IMPLICATIONS FOR TUMOR BIOLOGY AND THERAPY

Ewing sarcoma family of tumors (ESFT) is a group of aggressive pediatric malignancies driven by the EWS-FLI1 fusion protein, an aberrant transcription factor up-regulating specific target genes, such as neuropeptide Y (NPY) and its Y1 and Y5 receptors (Y5Rs). Previously, we have shown that both exog...

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Autori principali: Lu, Congyi, Tilan, Jason U., Everhart, Lindsay, Czarnecka, Magdalena, Soldin, Steven J., Mendu, Damodara R., Jeha, Dima, Hanafy, Jailan, Lee, Christina K., Sun, Junfeng, Izycka-Swieszewska, Ewa, Toretsky, Jeffrey A., Kitlinska, Joanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149342/
https://ncbi.nlm.nih.gov/pubmed/21680731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224089
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