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Disaccharide Binding to Galectin-1: Free Energy Calculations and Molecular Recognition Mechanism
Galectin-1, a member of the conserved family of carbohydrate-binding proteins with affinity for β-galactosides, is a key modulator of diverse cell functions such as immune response and regulation. The binding affinity and specificity of galectin-1 for eight different β-galactosyl terminal disacchari...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149269/ https://ncbi.nlm.nih.gov/pubmed/21539798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.03.032 |
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