The immunoreceptor adapter protein DAP12 suppresses B lymphocyte–driven adaptive immune responses

DAP12, an immunoreceptor tyrosine-based activation motif–bearing adapter protein, is involved in innate immunity mediated by natural killer cells and myeloid cells. We show that DAP12-deficient mouse B cells and B cells from a patient with Nasu-Hakola disease, a recessive genetic disorder resulting...

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Autores principales: Nakano-Yokomizo, Takako, Tahara-Hanaoka, Satoko, Nakahashi-Oda, Chigusa, Nabekura, Tsukasa, Tchao, Nadia K., Kadosaki, Momoko, Totsuka, Naoya, Kurita, Naoki, Nakamagoe, Kiyotaka, Tamaoka, Akira, Takai, Toshiyuki, Yasui, Teruhito, Kikutani, Hitoshi, Honda, Shin-ichiro, Shibuya, Kazuko, Lanier, Lewis L., Shibuya, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149228/
https://ncbi.nlm.nih.gov/pubmed/21727189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101623
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