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The role for estrogen receptor-alpha and prolactin receptor in sex-dependent DEN-induced liver tumorigenesis
Mice treated neonatally with diethylnitrosamine (DEN) develop liver tumors in a male-dominant manner, reflecting the male bias in human hepatocellular carcinoma. Evidence suggests that estrogen, androgen, prolactin (PRL) and growth hormone (GH) modify liver tumorigenesis. We determined the roles of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149205/ https://ncbi.nlm.nih.gov/pubmed/21606321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr094 |
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