CD8(+) T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity

Although immunodominance of CD8(+) T-cell responses is a well-recognised feature of viral infections, its role in responses to more antigenically complex pathogens is less clear. In previous studies we have observed that CD8(+) T-cell responses to Theileria parva exhibit different patterns of parasi...

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Autors principals: MacHugh, Niall D, Connelley, Timothy, Graham, Simon P, Pelle, Roger, Formisano, Principia, Taracha, Evans L, Ellis, Shirley A, McKeever, Declan J, Burrells, Alison, Morrison, W Ivan
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2009
Matèries:
Immunity to Infection
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149124/
https://ncbi.nlm.nih.gov/pubmed/19670382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939227
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