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Genome-wide Characterization of miR-34a Induced Changes in Protein and mRNA Expression by a Combined Pulsed SILAC and Microarray Analysis

The gene encoding the miR-34a microRNA is a transcriptional target of the p53 tumor suppressor protein and subject to epigenetic inactivation in colorectal cancer and numerous other tumor types. Here, we combined pulsed SILAC (pSILAC) and microarray analyses to identify miR-34a-induced changes in pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Kaller, Markus, Liffers, Sven-Thorsten, Oeljeklaus, Silke, Kuhlmann, Katja, Röh, Simone, Hoffmann, Reinhard, Warscheid, Bettina, Hermeking, Heiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149097/
https://ncbi.nlm.nih.gov/pubmed/21566225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.010462
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