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Uncoordinated Loss of Chromatid Cohesion Is a Common Outcome of Extended Metaphase Arrest
Chromosome segregation requires coordinated separation of sister chromatids following biorientation of all chromosomes on the mitotic spindle. Chromatid separation at the metaphase-to-anaphase transition is accomplished by cleavage of the cohesin complex that holds chromatids together. Here we show...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149067/ https://ncbi.nlm.nih.gov/pubmed/21829677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022969 |
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