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Modulation of Pancreatic Cancer Chemoresistance by Inhibition of TAK1
BACKGROUND: TGF-β-activated kinase-1 (TAK1), a mitogen-activated protein kinase kinase kinase, functions in the activation of nuclear factor κB (NF-κB) and activator protein-1, which can suppress proapoptotic signaling pathways and thus promote resistance to chemotherapeutic drugs. However, it is no...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149044/ https://ncbi.nlm.nih.gov/pubmed/21743023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr243 |
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