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Structural and functional basis for RNA cleavage by Ire1
BACKGROUND: The unfolded protein response (UPR) controls the protein folding capacity of the endoplasmic reticulum (ER). Central to this signaling pathway is the ER-resident bifunctional transmembrane kinase/endoribonuclease Ire1. The endoribonuclease (RNase) domain of Ire1 initiates a non-conventio...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149027/ https://ncbi.nlm.nih.gov/pubmed/21729333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-47 |
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