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BMP signaling balances proliferation and differentiation of muscle satellite cell descendants

BACKGROUND: The capacity of muscle to grow or to regenerate after damage is provided by adult stem cells, so called satellite cells, which are located under the basement lamina of each myofiber. Upon activation satellite cells enter the cell cycle, proliferate and differentiate into myoblasts, which...

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Autores principales: Friedrichs, Melanie, Wirsdöerfer, Florian, Flohé, Stefanie B, Schneider, Sabine, Wuelling, Manuela, Vortkamp, Andrea
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149017/
https://ncbi.nlm.nih.gov/pubmed/21645366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-12-26
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