An Integrated Mathematical Model of Thrombin-, Histamine-and VEGF-Mediated Signalling in Endothelial Permeability

BACKGROUND: Endothelial permeability is involved in injury, inflammation, diabetes and cancer. It is partly regulated by the thrombin-, histamine-, and VEGF-mediated myosin-light-chain (MLC) activation pathways. While these pathways have been investigated, questions such as temporal effects and the...

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Main Authors: Wei, XN, Han, BC, Zhang, JX, Liu, XH, Tan, CY, Jiang, YY, Low, BC, Tidor, B, Chen, YZ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149001/
https://ncbi.nlm.nih.gov/pubmed/21756365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-112
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