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Chronic hypoxia impairs murine hippocampal development and depletes the postnatal progenitor pool by attenuating mTOR signaling
Chronic hypoxia (CH) is a major risk factor for impaired cognitive function in various disease states, particularly in the context of cyanotic congenital heart disease. While most brain development occurs prenatally, the dentate gyrus (DG) of the hippocampus harbors progenitor stem cells that contri...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148804/ https://ncbi.nlm.nih.gov/pubmed/21532529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3182218622 |
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