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Knockout of Toll-like Receptor-2 attenuates both the Pro-Inflammatory State of Diabetes and Incipient Diabetic Nephropathy

OBJECTIVE: Type 1 Diabetes (T1DM) is a proinflammatory state and confers an increased risk for vascular complications. Toll-like receptors (TLR) could participate in diabetic vasculopathies. Whether TLR activation contributes to the proinflammatory state of T1DM and the pathogenesis of diabetic neph...

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Detalhes bibliográficos
Main Authors: Devaraj, Sridevi, Tobias, Peter, Kasinath, Balakuntalam S., Ramsamooj, Rajendra, Afify, Alaa, Jialal, Ishwarlal
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148786/
https://ncbi.nlm.nih.gov/pubmed/21617141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.228924
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