Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

During seasonal influenza epidemics, disease burden is shouldered predominantly by the very young and the elderly. Elderly individuals are particularly affected, in part because vaccine efficacy wanes with age. This has been linked to a reduced ability to induce a robust serum antibody response. Her...

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Detalhes bibliográficos
Main Authors: Sasaki, Sanae, Sullivan, Meghan, Narvaez, Carlos F., Holmes, Tyson H., Furman, David, Zheng, Nai-Ying, Nishtala, Madhuri, Wrammert, Jens, Smith, Kenneth, James, Judith A., Dekker, Cornelia L., Davis, Mark M., Wilson, Patrick C., Greenberg, Harry B., He, Xiao-Song
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148747/
https://ncbi.nlm.nih.gov/pubmed/21785218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57834
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