Cell cycle–related kinase is a direct androgen receptor–regulated gene that drives β-catenin/T cell factor–dependent hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. It is more prevalent in men than women. Related to this, recent genetic studies have revealed a causal role for androgen receptor (AR) in hepatocarcinogenesis, but the underlying molecular mechanism remains unclear. Here, we u...

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Detalhes bibliográficos
Main Authors: Feng, Hai, Cheng, Alfred S.L., Tsang, Daisy P., Li, May S., Go, Minnie Y., Cheung, Yue S., Zhao, Gui-jun, Ng, Samuel S., Lin, Marie C., Yu, Jun, Lai, Paul B., To, Ka F., Sung, Joseph J.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148736/
https://ncbi.nlm.nih.gov/pubmed/21747169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45967
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