Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production

Accumulating evidence suggests that mesenchymal stem cells (MSCs) are recruited to the tumor microenvironment; however, controversy exists regarding their role in solid tumors. In this study, we identified and confirmed the presence of carcinoma-associated MSCs (CA-MSCs) in the majority of human ova...

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Autori principali: McLean, Karen, Gong, Yusong, Choi, Yunjung, Deng, Ning, Yang, Kun, Bai, Shoumei, Cabrera, Lourdes, Keller, Evan, McCauley, Laurie, Cho, Kathleen R., Buckanovich, Ronald J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148732/
https://ncbi.nlm.nih.gov/pubmed/21737876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45273
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