Rituximab-Induced Depletion of Anti-PLA(2)R Autoantibodies Predicts Response in Membranous Nephropathy

Autoantibodies to the M-type phospholipase A(2) receptor (PLA(2)R) are sensitive and specific for idiopathic membranous nephropathy. The anti-B cell agent rituximab is a promising therapy for this disease, but biomarkers of early response to treatment currently do not exist. Here, we investigated wh...

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Detalhes bibliográficos
Main Authors: Beck, Laurence H., Fervenza, Fernando C., Beck, David M., Bonegio, Ramon G.B., Malik, Fahim A., Erickson, Stephen B., Cosio, Fernando G., Cattran, Daniel C., Salant, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148709/
https://ncbi.nlm.nih.gov/pubmed/21784898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010111125
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