Aurora Kinase A expression is associated with lung cancer histological-subtypes and with tumor de-differentiation

BACKGROUND: Aurora kinase A (AURKA) is a member of serine/threonine kinase family. Several kinases belonging to this family are activated in the G2/M phase of the cell cycle being involved in mitotic chromosomal segregation. AURKA overexpression is significantly associated with neoplastic transforma...

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Bibliografiske detaljer
Main Authors: Lo Iacono, Marco, Monica, Valentina, Saviozzi, Silvia, Ceppi, Paolo, Bracco, Enrico, Papotti, Mauro, Scagliotti, Giorgio V
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148570/
https://ncbi.nlm.nih.gov/pubmed/21718475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-100
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