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Mitochondrial Stress: A Bridge between Mitochondrial Dysfunction and Metabolic Diseases?
Under pathophysiological conditions such as obesity, excessive oxidation of nutrients may induce mitochondrial stress, leading to mitochondrial unfolded protein response (UPR(mt)) and initiation of a retrograde stress signaling pathway. Defects in the UPR(mt) and the retrograde signaling pathways ma...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148404/ https://ncbi.nlm.nih.gov/pubmed/21616143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.05.008 |
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