18F-fluorodeoxy-glucose positron emission tomography (18FDG-PET) marks MYC-overexpressing human basal-like breast cancers

In contrast to normal cells, cancer cells avidly take up glucose and metabolize it to lactate even when oxygen is abundant, a phenomenon referred to as the Warburg effect. This fundamental alteration in glucose metabolism in cancer cells enables their specific detection by Positron Emission Tomograp...

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Main Authors: Palaskas, Nicolaos, Larson, Steven M., Schultz, Nikolaus, Komisopoulou, Evangelia, Wong, Justin, Rohle, Dan, Campos, Carl, Yannuzzi, Nicolas, Osborne, Joseph R., Linkov, Irina, Kastenhuber, Edward R., Taschereau, Richard, Plaisier, Seema B., Tran, Chris, Heguy, Adriana, Wu, Hong, Sander, Chris, Phelps, Michael E., Brennan, Cameron, Port, Elisa, Huse, Jason T., Graeber, Thomas G., Mellinghoff, Ingo K.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148325/
https://ncbi.nlm.nih.gov/pubmed/21646475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4633
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