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RNA interference-produced autoregulation of inducible nitric oxide synthase expression

Vector-mediated delivery of short-hairpin RNA (shRNA) to regulate gene expression holds a great therapeutic promise. We hypothesize that gene expression can be autoregulated with RNA interference. We used inducible nitric oxide synthase (iNOS) as a gene model to test this hypothesis. Lipopolysacchar...

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Détails bibliographiques
Auteurs principaux: Feng, Chenzhuo, Cao, Lin, Zuo, Zhiyi
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148287/
https://ncbi.nlm.nih.gov/pubmed/21741974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.06.032
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