Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis

STAT3, an essential transcription factor with pleiotropic functions, plays critical roles in the pathogenesis of autoimmunity. Despite recent data linking STAT3 with inflammatory bowel disease, exactly how it contributes to chronic intestinal inflammation is not known. Using a T cell transfer model...

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Main Authors: Durant, Lydia, Watford, Wendy T., Ramos, Haydeé L., Laurence, Arian, Vahedi, Golnaz, Wei, Lai, Takahashi1, Hayato, Sun, Hong-Wei, Kanno, Yuka, Powrie, Fiona, O'Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148263/
https://ncbi.nlm.nih.gov/pubmed/20493732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.05.003
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