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An In Vivo Murine Model of Low Magnitude Oscillatory Wall Shear Stress to Address the Molecular Mechanisms of Mechanotransduction

OBJECTIVE: Current understanding of shear sensitive signaling pathways has primarily been studied in vitro largely due to a lack of adequate in vivo models. Our objective was to develop a simple and well characterized murine aortic coarctation model to acutely alter the hemodynamic environment in vi...

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Bibliografiset tiedot
Päätekijät: Willett, Nick J., Long, Robert C., Maiellaro-Rafferty, Kathryn, Sutliff, Roy L., Schafer, Richard, Oshinski, John N., Giddens, Don P., Guldberg, Robert E., Taylor, W. Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148257/
https://ncbi.nlm.nih.gov/pubmed/20705917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.211532
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