TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding

The receptor for advanced glycation end products (RAGE) is thought to be involved in the pathogenesis of a broad range of inflammatory, degenerative and hyperproliferative diseases. It binds to diverse ligands and activates multiple intracellular signaling pathways. Despite these pivotal functions,...

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Bibliographic Details
Main Authors: Sakaguchi, Masakiyo, Murata, Hitoshi, Yamamoto, Ken-ichi, Ono, Tomoyuki, Sakaguchi, Yoshihiko, Motoyama, Akira, Hibino, Toshihiko, Kataoka, Ken, Huh, Nam-ho
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148248/
https://ncbi.nlm.nih.gov/pubmed/21829704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023132
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