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Paradoxical Regulation of Human FGF21 by Both Fasting and Feeding Signals: Is FGF21 a Nutritional Adaptation Factor?

Fibroblast growth factor 21 (FGF21) has recently emerged as a metabolic hormone involved in regulating glucose and lipid metabolism in mouse, but the regulatory mechanisms and actions of FGF21 in humans remain unclear. Here we have investigated the regulatory mechanisms of the human FGF21 gene at th...

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Detalhes bibliográficos
Main Authors: Uebanso, Takashi, Taketani, Yutaka, Yamamoto, Hironori, Amo, Kikuko, Ominami, Hirokazu, Arai, Hidekazu, Takei, Yuichiro, Masuda, Masashi, Tanimura, Ayako, Harada, Nagakatsu, Yamanaka-Okumura, Hisami, Takeda, Eiji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148241/
https://ncbi.nlm.nih.gov/pubmed/21829679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022976
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