Pulsatile ex vivo perfusion of human saphenous vein grafts under controlled pressure conditions increases MMP-2 expression

BACKGROUND: The use of human saphenous vein grafts (HSVGs) as a bypass conduit is a standard procedure in the treatment of coronary artery disease while their early occlusion remains a major problem. METHODS: We have developed an ex vivo perfusion system, which uses standardized and strictly control...

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Main Authors: Dummler, Sara, Eichhorn, Stefan, Tesche, Christian, Schreiber, Ulrich, Voss, Bernhard, Deutsch, Marcus-André, Hauner, Hans, Lahm, Harald, Lange, Rüdiger, Krane, Markus
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148203/
https://ncbi.nlm.nih.gov/pubmed/21777461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-925X-10-62
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