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Deletion of Adam10 in endothelial cells leads to defects in organ-specific vascular structures
During vertebrate angiogenesis, Notch regulates the cell-fate decision between vascular tip cells versus stalk cells. Canonical Notch signaling depends on sequential proteolytic events, whereby interaction of Notch with membrane-anchored ligands triggers proteolytic processing, first by Adam10 and t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148163/ https://ncbi.nlm.nih.gov/pubmed/21652679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-348557 |
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