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RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG

ERG is a member of the ETS transcription factor family that is highly enriched in endothelial cells (ECs). To further define the role of ERG in regulating EC function, we evaluated the effect of ERG knock-down on EC lumen formation in 3D collagen matrices. Blockade of ERG using siRNA completely inte...

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Hlavní autoři: Yuan, Lei, Sacharidou, Anastasia, Stratman, Amber N., Le Bras, Alexandra, Zwiers, Peter J., Spokes, Katherine, Bhasin, Manoj, Shih, Shou-ching, Nagy, Janice A., Molema, Grietje, Aird, William C., Davis, George E., Oettgen, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Vascular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148162/
https://ncbi.nlm.nih.gov/pubmed/21628409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-315275
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