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Fast and Accurate Calculation of a Computationally Intensive Statistic for Mapping Disease Genes

Many statistical methods in biology utilize numerical integration in order to deal with moderately high-dimensional parameter spaces without closed form integrals. One such method is the PPL, a class of models for mapping and modeling genes for complex human disorders. While the most common approach...

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Detalhes bibliográficos
Main Authors: Seok, Sang-Cheol, Evans, Michael, Vieland, Veronica J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148122/
https://ncbi.nlm.nih.gov/pubmed/19432537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2008.0175
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