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Improved synthesis of DOTA tetraamide lanthanide(III) ligands: tool for increasing the repertoire of potential PARACEST contrast agents for MRI and/or fluorescent sensors

The synthesis of new DOTA tetra-amide (DOTAMR(4)) compounds is of great interest given their application in the formation of Ln(III) complexes which are potential PARACEST contrast agents in MRI or fluorescent molecular probes. In this context amino acid and peptide DOTAMR(4) derivatives are particu...

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Main Authors: De León-Rodríguez, Luis M., Viswanathan, Subha, Sherry, A. Dean
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148078/
https://ncbi.nlm.nih.gov/pubmed/20586036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmmi.371
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