Neutralizing Anti-gH Antibody of Varicella-Zoster Virus Modulates Distribution of gH and Induces Gene Regulation, Mimicking Latency

The anti-glycoprotein H (gH) monoclonal antibody (anti-gH-MAb) that neutralizes varicella-zoster virus (VZV) inhibited cell-to-cell infection, resulting in a single infected cell without apoptosis or necrosis, and the number of infectious cells in cultures treated with anti-gH-MAb declined to undete...

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Bibliographic Details
Main Authors: Shiraki, Kimiyasu, Daikoku, Tohru, Takemoto, Masaya, Yoshida, Yoshihiro, Suzuki, Kazuhiro, Akahori, Yasushi, Okuno, Toshiomi, Kurosawa, Yoshikazu, Asano, Yoshizo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147995/
https://ncbi.nlm.nih.gov/pubmed/21632752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00435-11
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