The Genetic Bottleneck in Vertical Transmission of Subtype C HIV-1 Is Not Driven by Selection of Especially Neutralization-Resistant Virus from the Maternal Viral Population

Subtype C human immunodeficiency virus type 1 (HIV-1C) continues to cause the majority of new cases of mother-to-child transmission (MTCT), and yet there are limited data on HIV-1C transmission. We amplified env from plasma RNA for 19 HIV-1C MTCT pairs, 10 transmitting in utero (IU) and 9 transmitti...

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Detalhes bibliográficos
Main Authors: Russell, Elizabeth S., Kwiek, Jesse J., Keys, Jessica, Barton, Kirston, Mwapasa, Victor, Montefiori, David C., Meshnick, Steven R., Swanstrom, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147968/
https://ncbi.nlm.nih.gov/pubmed/21593171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00197-11
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