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Analysis of Rab GTPase-Activating Proteins Indicates that Rab1a/b and Rab43 Are Important for Herpes Simplex Virus 1 Secondary Envelopment

Assembly of herpes simplex virus 1 (HSV-1) occurs in the cytoplasm, where the capsid and tegument bud into host cell membranes. It is at this point that the viral glycoproteins are incorporated into the virion, as they are located at the assembly site. We investigated the role of the Rab GTPases in...

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Main Authors: Zenner, Helen L., Yoshimura, Shin-ichiro, Barr, Francis A., Crump, Colin M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147948/
https://ncbi.nlm.nih.gov/pubmed/21680502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00500-11
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