Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss)

The retinoic acid-inducible gene I (RIG-I)-like receptors (RLR) comprise three homologues: RIG-I, melanoma differentiation-associated gene 5 (MDA5), and laboratory of genetics and physiology 2 (LGP2). They activate the host interferon (IFN) system upon recognition of viral RNA pathogen-associated mo...

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Hlavní autoři: Chang, Mingxian, Collet, Bertrand, Nie, Pin, Lester, Katherine, Campbell, Scott, Secombes, Christopher J., Zou, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147945/
https://ncbi.nlm.nih.gov/pubmed/21680521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00445-10
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