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Impact of Intra- and Interspecies Variation of Occludin on Its Function as Coreceptor for Authentic Hepatitis C Virus Particles

Hepatitis C virus (HCV) is characterized by a narrow host range and high interindividual variability in the clinical course of infection. Both of these traits are thought to be largely due to genetic variation between species and between individual hosts. The tight junction component occludin (OCLN)...

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Autors principals: Ciesek, Sandra, Westhaus, Sandra, Wicht, Melanie, Wappler, Ilka, Henschen, Sylvana, Sarrazin, Christoph, Hamdi, Nabila, Abdelaziz, Ahmed I., Strassburg, Christian P., Wedemeyer, Heiner, Manns, Michael P., Pietschmann, Thomas, von Hahn, Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147936/
https://ncbi.nlm.nih.gov/pubmed/21632765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00212-11
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