Establishment of the Black-Tailed Prairie Dog (Cynomys ludovicianus) as a Novel Animal Model for Comparing Smallpox Vaccines Administered Preexposure in both High- and Low-Dose Monkeypox Virus Challenges

The 2003 monkeypox virus (MPXV) outbreak and subsequent laboratory studies demonstrated that the black-tailed prairie dog is susceptible to MPXV infection and that the ensuing rash illness is similar to human systemic orthopoxvirus (OPXV) infection, including a 7- to 9-day incubation period and, lik...

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Detalhes bibliográficos
Main Authors: Keckler, M. S., Carroll, D. S., Gallardo-Romero, N. F., Lash, R. R., Salzer, J. S., Weiss, S. L., Patel, N., Clemmons, C. J., Smith, S. K., Hutson, C. L., Karem, K. L., Damon, I. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147922/
https://ncbi.nlm.nih.gov/pubmed/21632764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02174-10
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