Ultrasensitive Detection of Drug-Resistant Pandemic 2009 (H1N1) Influenza A Virus by Rare-Variant-Sensitive High-Resolution Melting-Curve Analysis

Oseltamivir (Tamiflu), an oral neuraminidase inhibitor, has been widely used to treat pandemic 2009 (H1N1) influenza A. Although a majority of 2009 (H1N1) influenza A virus remains oseltamivir susceptible, the threat of resistance due to the His275Tyr mutation is highlighted by the limitations of al...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Neng, Pinsky, Benjamin A., Lee, Betty P., Lin, Min, Schrijver, Iris
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Virology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147852/
https://ncbi.nlm.nih.gov/pubmed/21543559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00277-11
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