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Mutation Analysis of SLC26A4 for Pendred Syndrome and Nonsyndromic Hearing Loss by High-Resolution Melting

Pendred syndrome and DFNB4 (autosomal recessive nonsyndromic congenital deafness, locus 4) are associated with autosomal recessive congenital sensorineural hearing loss and mutations in the SLC26A4 gene. Extensive allelic heterogeneity, however, necessitates analysis of all exons and splice sites to...

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Detalhes bibliográficos
Main Authors: Chen, Neng, Tranebjærg, Lisbeth, Rendtorff, Nanna Dahl, Schrijver, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123795/
https://ncbi.nlm.nih.gov/pubmed/21704276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.03.003
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