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Combined Deletions of pfhrp2 and pfhrp3 Genes Result in Plasmodium falciparum Malaria False-Negative Rapid Diagnostic Test

We report a case of misdiagnosis of Plasmodium falciparum malaria from Brazil with negative PfHRP2-based rapid diagnostic tests (RDTs), leading to inappropriate case management. Genetic tests showed the deletion of both pfhrp2 and pfhrp3 genes. The detection of two distinct P. falciparum target anti...

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Hlavní autoři: Houzé, Sandrine, Hubert, Véronique, Le Pessec, Gaëlle, Le Bras, Jacques, Clain, Jérôme
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147824/
https://ncbi.nlm.nih.gov/pubmed/21543573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00281-11
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