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Identification of Amino Acid Residues Critical for Catalysis of Holliday Junction Resolution by Mycoplasma genitalium RecU

The RecU protein from Mycoplasma genitalium, RecU(Mge), is a 19.4-kDa Holliday junction (HJ) resolvase that binds in a nonspecific fashion to HJ substrates and, in the presence of Mn(2+), cleaves these substrates at a specific sequence (5′-G/TC↓C/TTA/GG-3′). To identify amino acid residues that are...

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Main Authors: Sluijter, Marcel, Aslam, Mohammad, Hartwig, Nico G., van Rossum, Annemarie M. C., Vink, Cornelis
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147543/
https://ncbi.nlm.nih.gov/pubmed/21642467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00247-11
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