Development of an Automated, High-Throughput Bactericidal Assay That Measures Cellular Respiration as a Survival Readout for Neisseria meningitidis

Complement-mediated bactericidal activity has long been regarded as the serological correlate of protective immunity against Neisseria meningitidis. This was affirmed in 2005 at a WHO-sponsored meningococcal serology standardization workshop. The assay currently employed by most laboratories involve...

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Autores principales: Mak, Puiying A., Santos, George F., Masterman, Kelly-Anne, Janes, Jeff, Wacknov, Bill, Vienken, Kay, Giuliani, Marzia, Herman, Ann E., Cooke, Michael, Mbow, M. Lamine, Donnelly, John
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
Materias:
Vaccine Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147359/
https://ncbi.nlm.nih.gov/pubmed/21715580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05028-11
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