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WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways

An epithelial sheet, the epicardium, lines the surface of the heart. In the developing embryo, the epicardium expresses the transcriptional regulator Wilm’s Tumor Gene 1 (Wt1). Through incompletely understood mechanisms, Wt1 inactivation derails normal heart development. We investigated mechanisms b...

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Bibliografische gegevens
Hoofdauteurs: von Gise, Alexander, Zhou, Bin, Honor, Leah B., Ma, Qing, Petryk, Anna, Pu, William T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147112/
https://ncbi.nlm.nih.gov/pubmed/21663736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.05.668
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