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WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways
An epithelial sheet, the epicardium, lines the surface of the heart. In the developing embryo, the epicardium expresses the transcriptional regulator Wilm’s Tumor Gene 1 (Wt1). Through incompletely understood mechanisms, Wt1 inactivation derails normal heart development. We investigated mechanisms b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147112/ https://ncbi.nlm.nih.gov/pubmed/21663736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.05.668 |
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