Association of Rad51 polymorphism with DNA repair in BRCA1 mutation carriers and sporadic breast cancer risk

BACKGROUND: Inter-individual variation in DNA repair capacity is thought to modulate breast cancer risk. The phenotypic mutagen sensitivity assay (MSA) measures DNA strand breaks in lymphocytes; women with familial and sporadic breast cancers have a higher mean number of breaks per cell (MBPC) then...

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Detalhes bibliográficos
Main Authors: Ricks-Santi, Luisel J, Sucheston, Lara E, Yang, Yang, Freudenheim, Jo L, Isaacs, Claudine J, Schwartz, Marc D, Dumitrescu, Ramona G, Marian, Catalin, Nie, Jing, Vito, Dominica, Edge, Stephen B, Shields, Peter G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146938/
https://ncbi.nlm.nih.gov/pubmed/21708019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-278
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