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Exploring the selective constraint on the sizes of insertions and deletions in 5' untranslated regions in mammals

BACKGROUND: Small insertions and deletions ("indels" with size ≦ 100 bp) whose lengths are not multiples of three (non-3n) are strongly constrained and depleted in protein-coding sequences. Such a constraint has never been reported in noncoding genomic regions. In 5'untranslated regio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Chun-Hsi, Liao, Ben-Yang, Chen, Feng-Chi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146882/
https://ncbi.nlm.nih.gov/pubmed/21726469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-192
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