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The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design

BACKGROUND: Streptococcus pneumoniae is a globally important pathogen. The Gram-positive diplococcus is a leading cause of pneumonia, otitis media, bacteremia, and meningitis, and antibiotic resistant strains have become increasingly common over recent years. Alanine racemase is a ubiquitous enzyme...

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Main Authors: Im, Hookang, Sharpe, Miriam L, Strych, Ulrich, Davlieva, Milya, Krause, Kurt L
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146814/
https://ncbi.nlm.nih.gov/pubmed/21612658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-11-116
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