Variants of the Caveolin-1 Gene: A Translational Investigation Linking Insulin Resistance and Hypertension

CONTEXT: The co-occurrence of insulin resistance (IR) and hypertension is a heritable condition leading to cardiovascular complications. Caveolin-1 (CAV1), a gene previously associated with metabolic dysfunction in animal and cellular models, may be a marker for these conditions in humans. OBJECTIVE...

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Hauptverfasser: Pojoga, Luminita H., Underwood, Patricia C., Goodarzi, Mark O., Williams, Jonathan S., Adler, Gail K., Jeunemaitre, Xavier, Hopkins, Paul N., Raby, Benjamin A., Lasky-Su, Jessica, Sun, Bei, Cui, Jinrui, Guo, Xiuqing, Taylor, Kent D., Chen, Yii-Der Ida, Xiang, Anny, Raffel, Leslie J., Buchanan, Thomas A., Rotter, Jerome I., Williams, Gordon H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2011
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JCEM Online: Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146791/
https://ncbi.nlm.nih.gov/pubmed/21613355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2738
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